CRYAA 抗体 (AA 1-173)
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Quick Overview for CRYAA 抗体 (AA 1-173) (ABIN165392)
抗原
See all CRYAA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-173
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原理
- Human Crystallin alpha A/CRYAA antibody
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纯化方法
- Purified
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免疫原
- Recombinant human Crystallin alpha A (1-173aa) purified from E. coli
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亚型
- IgG1 kappa
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应用备注
- Recommended dilution 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- CRYAA (Crystallin, alpha A (CRYAA))
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别名
- Crystallin alpha A/CRYAA
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背景
- Alpha-crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency, which are composed of two gene products alpha-A and alpha-B, for acidic and basic, respectively. alpha-crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They act as molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weight aggregates. These heterogeneous aggregates consist of 30-40 subunits of the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and the participation in the intracellular architecture.
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NCBI登录号
- NP_000385
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途径
- M Phase
抗原
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