KMO 抗体 (AA 300-400)
Quick Overview for KMO 抗体 (AA 300-400) (ABIN1607892)
抗原
See all KMO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-400
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Supplier Product No.
- 600-401-j25
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Supplier
- Rockland
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原理
- Kmo Antibody
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交叉反应 (详细)
- This antibody is specific towards Kynurenine 3-monooxygenase (KMO).
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产品特性
- Synonyms: rabbit anti-KMO antibody, kynurenine 3-monooxygenase, kynurenine 3-hydroxylase
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纯化方法
- Anti-KMO was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: KMO affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region surrounding 300-400aa of the mouse KMO chain.
Immunogen Type: Conjugated Peptide
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应用备注
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Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-KMO antibody is tested for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~58 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.08 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 6 months
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- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
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别名
- KMO
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背景
- Background: Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid is a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Anti-KMO antibodies are ideal for researchers interested in Apoptosis, Neurodegeneration, and Neuroscience research.
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基因ID
- 8564
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NCBI登录号
- NP_003670
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UniProt
- O15229
抗原
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