Huntingtin 抗体 (C-Term)
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- 抗原 See all Huntingtin (HTT) 抗体
- Huntingtin (HTT)
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Huntingtin antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Fluorescence Microscopy (FM)
- Supplier Product No.
- 600-401-j24
- Supplier
- Rockland
- 原理
- Huntington Antibody
- 交叉反应 (详细)
- This antibody is specific towards HTT.
- 产品特性
- Synonyms: rabbit anti-Huntington antibody, rabbit anti-Huntingtin antibody, HD protein, HTT, Huntington Disease Protein, Huntington disease, IT15, LOMARS
- 纯化方法
- Anti-Huntingtin was affinity purified from monospecific antiserum by immunoaffinity chromatography.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: Huntington affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminus of human Huntington disease protein.
Immunogen Type: Conjugated Peptide
- Top Product
- Discover our top product HTT Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-Huntingtin antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~350 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 0.1 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 30 % Glycerol
Preservative: None - 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 6 months
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- 抗原
- Huntingtin (HTT)
- 别名
- HTT (HTT 产品)
- 背景
- Background: Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (HTT) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington's disease protein is ~350kD in size and is localized in the brain. Anti-Huntingtin antibodies are ideal for researchers interested in Apoptosis, Autophagy, Cytoskeleton, Neurodegeneration, Neuroscience, and Neuronal Cell Markers research.
- 基因ID
- 3064
- NCBI登录号
- NP_002102
- UniProt
- P42858
- 途径
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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