HDAC7 抗体 (N-Term)
Quick Overview for HDAC7 抗体 (N-Term) (ABIN1607889)
抗原
See all HDAC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-j22
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Supplier
- Rockland
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原理
- HDAC7 (N-terminus) Antibody
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交叉反应 （详细）
- This antibody is specific towards HDAC7.
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产品特性
- Synonyms: rabbit anti-HDAC-7 antibody, HDAC7, HDAC 7, HD 7 antibody, histone deacetylase 7 antibody, Histone deacetylase-7, HD7A antibody, histone deacetylase 7A antibody, Histone deacetylase-7A, HDAC7A, HDAC 7A, HDAC-7A, HD-7A
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纯化方法
- Anti-HDAC7 was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: HDAC7 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N terminal region of human HDAC7.
Immunogen Type: Conjugated Peptide
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anti-Histone Deacetylase 7 (HDAC7) (AA 1-276) antibody
HDAC7 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2B11-1C1 unconjugated
anti-Histone Deacetylase 7 (HDAC7) (C-Term) antibodyHDAC7 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (AA 400-500) antibodyHDAC7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (Tyr721) antibodyHDAC7 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (AA 1-276) antibodyHDAC7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (Internal Region) antibodyHDAC7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) antibodyHDAC7 适用: 人 WB 宿主: 兔 Monoclonal 3H7 unconjugated
anti-Histone Deacetylase 7 (HDAC7) (C-Term) antibodyHDAC7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (Ser155) antibodyHDAC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (pSer155) antibodyHDAC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-HDAC7 antibody has been tested by ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~103 kDa and isoforms at ~70, and 40 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.55 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 6 months
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- HDAC7 (Histone Deacetylase 7 (HDAC7))
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别名
- HDAC7
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背景
- Background: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription. Anti-HDAC7 antibodies are ideal for researches interested in Breast Cancer, Cancer, Cell Cycle and Replication, Chromatin Research, Epigenetics, and Histone Deacetylases research.
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基因ID
- 51564
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NCBI登录号
- NP_001091886
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UniProt
- Q8WUI4
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
抗原
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