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beta-2 Microglobulin 抗体 (Biotin)

B2M 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1607723
发货至: 中国
  • 抗原 See all beta-2 Microglobulin (B2M) 抗体
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    适用
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    克隆类型
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    多克隆
    标记
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    This beta-2 Microglobulin antibody is conjugated to Biotin
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应 (详细)
    Cross reactivity against b2-Microglobulin from other sources may occur but has not been specifically determined.
    纯度
    Anti-beta-2-Microglobulin antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Biotin, anti-Rabbit Serum as well as purified and partially purified b2-Microglobulin [Human Urine].
    内毒素水平
    Low Endotoxin : No
    免疫原
    Anti-Beta-2-Microglobulin Antibody was produced by repeated immunizations with beta-2-Microglobulin protein isolated from human urine.
    Immunogen Type: Native Protein
    亚型
    IgG
    Top Product
    Discover our top product B2M Primary Antibody
  • 应用备注
    Anti-beta-2-Microglobulin antibody is suitable for western blotting to detect a single band of the expected apparent molecular weight and for ELISA. Researchers should determine optimal titers for applications that are not stated below.
    ELISA Dilution: 1:2.000 - 1:10.000
    Immunohistochemistry Dilution: 1:500 - 1:3.000
    Western Blot Dilution: 1:1.000 - 1:5.000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    注意事项
    Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store vial at -20 °C or below prior to opening. This vial contains a relatively low volume of reagent (25 µL). To minimize loss of volume dilute 1:10 by adding 225 µL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below.
    有效期
    Expiration date is one (1) year from date of opening.
  • Keefe, Hwang, Huan, Mendelson, Yao, Courchesne, Saleh, Madhur, Levy: "Evidence for a Causal Role of the SH2B3-β2M Axis in Blood Pressure Regulation." in: Hypertension (Dallas, Tex. : 1979), Vol. 73, Issue 2, pp. 497-503, (2019) (PubMed).

  • 抗原
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    别名
    Beta-2-Microglobulin (B2M 产品)
    别名
    Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
    背景
    Anti-beta-2-Microglobulin Antibody detects beta-2-Microglobulin. Beta-2-microglobulin is a component of the class I major histocompatibility complex (MHC), which are present on all nucleated cells (excludes red blood cells). It is involved in the presentation of peptide antigens to the immune system. Beta-2-microglobulin associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Anti-beta-2-Microglobulin Antibody is ideal for investigators involved in Cell Signaling, Immunology and Cell Biology research. Synonyms: B2M antibody, Beta 2 microglobulin precursor antibody, Beta chain of mhc class 1 proteins antibody, Hdcma22p antibody
    基因ID
    567
    UniProt
    P61769
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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