电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CCBE1 抗体 (AA 159-251)

This anti-CCBE1 antibody is a 兔 多克隆 antibody detecting CCBE1 in WB 和 IF. Suitable for 人.
产品编号 ABIN1589917
发货至: 中国

Quick Overview for CCBE1 抗体 (AA 159-251) (ABIN1589917)

抗原

See all CCBE1 抗体
CCBE1 (Collagen and Calcium Binding EGF Domains 1 (CCBE1))

适用

  • 20
  • 7
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1

宿主

  • 19
  • 2

克隆类型

  • 21
多克隆

标记

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
This CCBE1 antibody is un-conjugated

应用范围

  • 21
  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 159-251

    原理

    ccbe1 antibody

    特异性

    Recombinant human ccbe1 (Tyr35-Pro406) derived from Sf9 insect cells

    产品特性

    Chromosomal location: 18q21.32

    纯化方法

    Protein A purified

    免疫原

    Highly pure (>98%) recombinant human ccbe1 (Cys159-Leu251) derived from E. coli.

    亚型

    IgG
  • 应用备注

    Western Blot: Use 2-5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS

    注意事项

    Centrifuge vial prior to opening. Avoid repeated freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    CCBE1 (Collagen and Calcium Binding EGF Domains 1 (CCBE1))

    别名

    ccbe1

    背景

    Collagen and calcium binding EGF domains 1, KIAA1983,The lymphatic system comprises a vascular system separate from the cardiovascular system, essential for immune responses, fluid homeostasis and fat absorption. Lymphatic vessels develop in a complex process termed lymphangiogenesis that involves budding, migration and proliferation of lymphatic endothelial progenitor cells. A few genes, such as FLT4, FOXC2 and SOX18, are known to be critically involved in lymph vessel formation in humans. Lymphedema, lymphangiectasias, mental retardation and unusual facial characteristics define the autosomal recessive Hennekam syndrome. Homozygosity mapping identified a critical chromosomal region containing ccbe1, encoding Collagen and Calcium-Binding EGF-domain-1, a secreted protein which is required for embryonic lymphangiogenesis in zebrafish. ccbe1 is not expressed in endothelial cells of lymph vessels, and it may be a component of the extracellular matrix. In zebrafish, ccbe1 expression was observed along the earliest migration routes of endothelial cells that sprout from the posterior cardinal vein and migrate circuitously before developing into lymphatic vessels. ccbe1 might therefore be involved in guidance of these migrating cells.

    基因ID

    147372

    NCBI登录号

    NM_133459, NP_597716

    UniProt

    Q6UXH8
You are here:
Chat with us!