LIF 抗体
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北京 101111
Quick Overview for LIF 抗体 (ABIN1589881)
抗原
See all LIF 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LIF antibody
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特异性
- Recombinant human LIF
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产品特性
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Chromosomal location: 22q12.2
Produced from sera of rabbits immunized with highly pure recombinant human Leukemina Inhibitory Factor (LIF) [Ser23 - Phe202, produced in E. coli]. -
纯化方法
- Anti-human LIF was purified by affinity chromatography with immobilized Protein A.
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免疫原
- Recombinant human LIF (ABIN1589656)
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亚型
- IgG
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应用备注
- Western Blot: Use 2-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- LIF (Leukemia Inhibitory Factor (LIF))
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别名
- LIF
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背景
- LIF, CDF, DIA, HILDA, MLPLI,Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78 % identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.
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基因ID
- 3976
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NCBI登录号
- NM_002309, NP_002300
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UniProt
- P15018
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途径
- JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
抗原
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