EMILIN2 抗体
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Quick Overview for EMILIN2 抗体 (ABIN1589876)
抗原
See all EMILIN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Emilin-2 antibody
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特异性
- Recombinant gC1q domain of EMILIN2
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产品特性
- Chromosomal location: 18p11.3
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纯化方法
- The IgG2b/kappa fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 μm filtered solution in phosphate-buffered saline (PBS).
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免疫原
- Recombinant gC1q domain of EMILIN2
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亚型
- IgG2, kappa
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应用备注
- Western Blot: Use 2-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))
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别名
- Emilin-2
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背景
- EMILIN2, FOAP-10, EMILIN-2,Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.
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基因ID
- 84034
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NCBI登录号
- NM_032048, NP_114437
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UniProt
- Q9BXX0
抗原
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