GLG1 抗体
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- 抗原 See all GLG1 抗体
- GLG1 (Golgi Glycoprotein 1 (GLG1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Recombinant human soluble ESL-1
- 亚型
- IgG
- Top Product
- Discover our top product GLG1 Primary Antibody
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- 应用备注
- Western Blot: use 1-5 µg/mL
- 说明
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Rabbit IG Polyclonal Antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Centrifuge vial prior to opening.
- 储存条件
- -20 °C
- 储存方法
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
- 有效期
- 6 months
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- 抗原
- GLG1 (Golgi Glycoprotein 1 (GLG1))
- 别名
- ESL-1 (GLG1 产品)
- 别名
- AI593353 antibody, AW537898 antibody, CFR antibody, CFR-1 antibody, ESL-1 antibody, MG-160 antibody, MG160 antibody, Selel antibody, ESL1 antibody, LTCP-1 antibody, golgi glycoprotein 1 antibody, Golgi apparatus protein 1 antibody, golgi apparatus protein 1 antibody, GLG1 antibody, LOC100175586 antibody, Glg1 antibody
- 背景
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E-Selectin ligand-1/ESL-1 (GLG1, Golgi complex-Localized Glycoprotein 1, CFR1, MG160 and Cysteine-rich FGF receptor) is a 150-160 kDa glycoprotein. The amino acid sequence of MG160, a membrane sialoglycoprotein of the medial cisternae of the rat Golgi apparatus, is more than 90 % identical with CFR, a fibroblast growth factor (FGF) binding protein of chicken membranes, and with ESL-1, a ligand for E-selectin of plasma membranes of myeloid cells, furthermore, MG160, isolated by immunoaffinity chromatography from rat brain membranes, binds to basic FGF. The protein has a large luminal domain composed of an initial Proline-Glutamine-rich segment, encoded by an uninterrupted exonic sequence of several CAG-CAA repeats. Expansion of CAG repeats has been implicated in the etiology of several neurodegenerative diseases. The Proline-Glutamine-rich segment is followed by 16 cysteine-rich repeats that contain five potential Asparagine-linked glycosylation sites, which are conserved in the human, rat, mouse, and chicken. The large extracellular domain of the protein is followed by a single transmembrane domain and a 13-amino-acid cytoplasmic carboxy-terminal tail, which is identical to that in the chicken, rat, and mouse. It is expressed in both Golgi and/or the cell membrane of multiple cell typs, including liver stellate cells, neurons, cardiac myocytes, monocytes and bronchial epithelial cells. In the blood, GLG1/ESL-1 collaborates with PSGL-1 to mediate leukocyte binding to endothelial cell surfaces
Synonyms: Golgi apparatus protein-1, E-selectin ligand-1, Cysteine-rich fibroblast growth factor receptor - NCBI登录号
- NP_001139138, NM_001145666
- UniProt
- Q92896
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