GLG1 抗体
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Quick Overview for GLG1 抗体 (ABIN1589833)
抗原
See all GLG1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ESL-1 antibody
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特异性
- Recombinant human soluble ESL-1
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纯化方法
- Protein A purified
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免疫原
- Recombinant human soluble ESL-1
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亚型
- IgG
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anti-Golgi Glycoprotein 1 (GLG1) (AA 1048-1145) antibody
GLG1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Golgi Glycoprotein 1 (GLG1) (AA 1152-1179), (C-Term) antibodyGLG1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB24297 unconjugated
anti-Golgi Glycoprotein 1 (GLG1) (C-Term) antibodyGLG1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Golgi Glycoprotein 1 (GLG1) antibodyGLG1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GLG1-970 unconjugated
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应用备注
- Western Blot: Use 1-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- GLG1 (Golgi Glycoprotein 1 (GLG1))
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别名
- ESL-1
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背景
- Golgi apparatus protein-1, E-selectin ligand-1, Cysteine-rich fibroblast growth factor receptor,E-Selectin ligand-1/ESL-1 (GLG1, Golgi complex-Localized Glycoprotein 1, CFR1, MG160 and Cysteine-rich FGF receptor) is a 150-160 kDa glycoprotein. The amino acid sequence of MG160, a membrane sialoglycoprotein of the medial cisternae of the rat Golgi apparatus, is more than 90 % identical with CFR, a fibroblast growth factor (FGF) binding protein of chicken membranes, and with ESL-1, a ligand for E-selectin of plasma membranes of myeloid cells, furthermore, MG160, isolated by immunoaffinity chromatography from rat brain membranes, binds to basic FGF. The protein has a large luminal domain composed of an initial Proline-Glutamine-rich segment, encoded by an uninterrupted exonic sequence of several CAG-CAA repeats. Expansion of CAG repeats has been implicated in the etiology of several neurodegenerative diseases. The Proline-Glutamine-rich segment is followed by 16 cysteine-rich repeats that contain five potential Asparagine-linked glycosylation sites, which are conserved in the human, rat, mouse, and chicken. The large extracellular domain of the protein is followed by a single transmembrane domain and a 13-amino-acid cytoplasmic carboxy-terminal tail, which is identical to that in the chicken, rat, and mouse. It is expressed in both Golgi and/or the cell membrane of multiple cell typs, including liver stellate cells, neurons, cardiac myocytes, monocytes and bronchial epithelial cells. In the blood, GLG1/ESL-1 collaborates with PSGL-1 to mediate leukocyte binding to endothelial cell surfaces
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基因ID
- 2734
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NCBI登录号
- NM_001145666, NP_001139138
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UniProt
- Q92896
抗原
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