KDM5D 抗体
The 兔 多克隆 anti-KDM5D antibody (ABIN1589829) specifically detects KDM5D in WB.
The antibody is reactive with 人 samples.
产品编号 ABIN1589829
发货至:
中国
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Quick Overview for KDM5D 抗体 (ABIN1589829)
抗原
See all KDM5D 抗体
KDM5D
(Lysine (K)-Specific Demethylase 5D (KDM5D))
适用
人
宿主
兔
克隆类型
多克隆
标记
This KDM5D antibody is un-conjugated
应用范围
Western Blotting (WB)
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原理
- SMCY/JARID1D antibody
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特异性
- Recombinant human SMCY
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产品特性
- Chromosomal location: Yq11, Yq11
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纯化方法
- Protein A purified
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免疫原
- Recombinant human SMCY
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 5D (KDM5D) (AA 127-230) antibody
KDM5D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Lysine (K)-Specific Demethylase 5D (KDM5D) (C-Term) antibodyKDM5D 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western Blot: Use 1-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))
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别名
- SMCY/JARID1D
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背景
- KDM5D lysine (K)-specific demethylase 5D, HY, HYA,H-Y antigen is defined as a male histocompatibility antigen that causes rejection of male skin grafts by female recipients of the same inbred strain of rodents. Male-specific, or H-Y antigen(s), are also detected by cytotoxic T cells and antibodies. H-Y antigen appears to be an integral part of the membrane of most male cells. In addition, H-Y antibodies detect a soluble form of H-Y that is secreted by the testis. The gene (Smcy/SMCY) coding for H-Y antigen detected by T cells has been cloned. It is expressed ubiquitously in male mice and humans, and encodes an epitope that triggers a specific T-cell response in vitro. Additional epitopes coded for by different Y-chromosomal genes are probably required in vivo for the rejection of male grafts by female hosts. The molecular nature of H-Y antigen detected by antibodies on most male cells is not yet known. Testis-secreted, soluble H-Y antigen, however, was found to be identical to Müllerian-inhibiting substance (MIS). MIS cross-reacts with H-Y antibodies and identical findings were obtained for soluble H-Y antigen and MIS, i.e., secretion by testicular Sertoli and, to a lesser degree, ovarian cells, binding to a gonad-specific receptor, induction of gonadal sex reversal in vitro and, in cattle, in vivo. H-Y antisera also detect a molecule or molecules associated with the heterogametic sex in non-mammalian vertebrates. Molecular data on this antigen or antigens are not yet available.
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基因ID
- 8284
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NCBI登录号
- NM_001146705, NP_001140177
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UniProt
- Q9BY66
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途径
- Warburg Effect
抗原
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