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VEGF-Apan (Peptide) (N-Term) 抗体

The 兔 多克隆 anti-VEGF-Apan (Peptide) antibody (ABIN1589724) specifically detects VEGF-Apan (Peptide) in IP 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN1589724
发货至: 中国
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Quick Overview for VEGF-Apan (Peptide) (N-Term) 抗体 (ABIN1589724)

抗原

VEGF-Apan (Peptide)

适用

宿主

克隆类型

多克隆

应用范围

Immunoprecipitation (IP), Western Blotting (WB)
  • 抗原表位

    N-Term

    原理

    VEGF-Apan (Peptide) antibody

    特异性

    N-terminal peptide (20aa) of native human VEGF165

    产品特性

    Chromosomal location: 6p12
    Produced from sera of rabbits immunized with a highly purified N-terminal peptide of human VEGF-A.

    纯化方法

    Anti-VEGF-A was purified by affinity chromatography with immobilized Protein A.

    免疫原

    N-terminal peptide (20aa) of native human VEGF165

    亚型

    IgG
  • 应用备注

    IP: Use 1-5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS

    注意事项

    Centrifuge vial prior to opening.

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    VEGF-Apan (Peptide)

    背景

    VEGFA, VPF, VEGF, MVCD1,Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF) or vasculotropin, is a homodimeric 34 - 42 kDa, heparin-binding glycoprotein with potent angiogenic, mitogenic and vascular permeability-enhancing activities specific for endothelial cells. Different isoforms can be generated by differential splicing (e.g. VEGF165). All eight cysteine residues involved in intra- and inter-chain disulfide bonds are conserved among these growth factors. A cDNA encoding a protein having a 53 % amino acid sequence homology in the PDGF-like region of VEGF has been isolated from a human placental cDNA library. This protein, named placenta growth factor (PlGF), is now recognized to be a member of the VEGF family of growth factors. Two receptor tyrosine kinases have been described as putative VEGF receptors. Flt-1 (fms-like tyrosine kinase), and KDR (kinase-insert-domain-containing receptor) proteins have been shown to bind VEGF-A with high affinity. In vitro, VEGF is a potent endothelial cell mitogen. The antibody is against the N-terminus and will recognize all VEGF-A isoforms.

    基因ID

    7422

    NCBI登录号

    NM_001171626, NP_001165097

    UniProt

    P15692
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