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VSNL1 抗体

VSNL1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 2D11 unconjugated
产品编号 ABIN1580471
发货至: 中国
  • 抗原 See all VSNL1 抗体
    VSNL1 (Visinin-Like 1 (VSNL1))
    适用
    • 68
    • 34
    • 15
    • 3
    • 1
    人, 小鼠, 大鼠, Cow
    宿主
    • 52
    • 11
    • 3
    • 2
    • 1
    小鼠
    克隆类型
    • 60
    • 9
    单克隆
    标记
    • 42
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VSNL1 antibody is un-conjugated
    应用范围
    • 57
    • 37
    • 34
    • 12
    • 10
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    纯化方法
    affinity purified antibody
    克隆位点
    2D11
    亚型
    IgG1
    Top Product
    Discover our top product VSNL1 Primary Antibody
  • 应用备注
    The antibody solution can be used at dilutions of 1:500-1:1,000 in immunofluorescence experiments. In western blotting using chemiluminescence it can be used at dilutions of 1:1,000-2,000.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4°C short term or -20°C long term.
  • 抗原
    VSNL1 (Visinin-Like 1 (VSNL1))
    别名
    Visinin-like protein 1 (VSNL1 产品)
    别名
    HLP3 antibody, HPCAL3 antibody, HUVISL1 antibody, VILIP antibody, VILIP-1 antibody, Nvp1 antibody, Ratnvp1 antibody, Vnsl1 antibody, MGC132057 antibody, MGC146004 antibody, VSNL1 antibody, si:dkey-15f12.11 antibody, si:dkey-30j22.11 antibody, zgc:103644 antibody, hlp3 antibody, vilip antibody, hpcal3 antibody, huvisl1 antibody, vilip-1 antibody, visinin like 1 antibody, visinin-like 1 antibody, visinin like 1 S homeolog antibody, visinin-like 1a antibody, visinin like 1 L homeolog antibody, VSNL1 antibody, Vsnl1 antibody, vsnl1.S antibody, vsnl1 antibody, vsnl1a antibody, vsnl1.L antibody
    背景
    Visinin was originally isolated biochemically from chicken retina as a major protein of about 24 kDa on SDS-PAGE. Following cloning and sequencing of visinin, several visinin like proteins were discovered by homology screening. One of these, Visinin-like protein 1 is a small Calcium binding protein which is very abundant in the nervous system and is found only in neurons, though different neurons have different levels of expression. It is particularly concentrated in cerebellar Purkinje cells, and tends to be most abundant in perikarya and dendrites. The protein was discovered independently by several groups and is therefore also sometimes known as hippocalcin-like protein 3, HLP3, HPCAL3, HUVISL1, VLP-1, VILIP and VILIP-1. The protein belongs to the large superfamly of calmodulin and paravalbumin type proteins which function by binding Calcium ions. Calcium binding alters the confomation of these proteins and allow them to interact with other binding partners, the properties of which they may alter. Visinin-like protein 1 has four EF hand domains, which are negatively charged helix-turn-helix peptides which are responsible for Calcium binding. Visinin-like protein 1 is 191 amino acids in size and has a molecular weight on SDS-PAGE of 22 kDa. The protein has recently been suggested to be a useful biomarker of Alzheimer's disease and traumatic brain injury. The HGNC name for this protein is VSNL1.
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