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VSNL1 抗体

This 小鼠 单克隆 anti-VSNL1 antibody (Clone 2D11) specifically detects VSNL1 in WB, IHC, ICC 和 IF. The antibody is reactive with 人, 小鼠, 大鼠 和 Cow samples.
产品编号 ABIN1580471
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VSNL1 抗体 (ABIN1580471)

抗原

See all VSNL1 抗体
VSNL1 (Visinin-Like 1 (VSNL1))

适用

  • 54
  • 34
  • 15
  • 3
  • 1
人, 小鼠, 大鼠, Cow

宿主

  • 43
  • 8
  • 2
  • 2
  • 1
小鼠

克隆类型

  • 50
  • 6
单克隆

标记

  • 36
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VSNL1 antibody is un-conjugated

应用范围

  • 45
  • 31
  • 27
  • 9
  • 8
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

2D11
  • 纯化方法

    affinity purified antibody

    亚型

    IgG1
  • 应用备注

    The antibody solution can be used at dilutions of 1:500-1:1,000 in immunofluorescence experiments. In western blotting using chemiluminescence it can be used at dilutions of 1:1,000-2,000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4°C short term or -20°C long term.
  • 抗原

    VSNL1 (Visinin-Like 1 (VSNL1))

    别名

    Visinin-like protein 1

    背景

    Visinin was originally isolated biochemically from chicken retina as a major protein of about 24 kDa on SDS-PAGE. Following cloning and sequencing of visinin, several visinin like proteins were discovered by homology screening. One of these, Visinin-like protein 1 is a small Calcium binding protein which is very abundant in the nervous system and is found only in neurons, though different neurons have different levels of expression. It is particularly concentrated in cerebellar Purkinje cells, and tends to be most abundant in perikarya and dendrites. The protein was discovered independently by several groups and is therefore also sometimes known as hippocalcin-like protein 3, HLP3, HPCAL3, HUVISL1, VLP-1, VILIP and VILIP-1. The protein belongs to the large superfamly of calmodulin and paravalbumin type proteins which function by binding Calcium ions. Calcium binding alters the confomation of these proteins and allow them to interact with other binding partners, the properties of which they may alter. Visinin-like protein 1 has four EF hand domains, which are negatively charged helix-turn-helix peptides which are responsible for Calcium binding. Visinin-like protein 1 is 191 amino acids in size and has a molecular weight on SDS-PAGE of 22 kDa. The protein has recently been suggested to be a useful biomarker of Alzheimer's disease and traumatic brain injury. The HGNC name for this protein is VSNL1.
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