ALDOC 抗体 (C-Term)
Quick Overview for ALDOC 抗体 (C-Term) (ABIN1580409)
抗原
See all ALDOC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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纯化方法
- affinity purified antibody
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亚型
- IgG1
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anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (N-Term) antibody
ALDOC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (AA 190-354) antibodyALDOC 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (AA 1-170) antibodyALDOC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) antibodyALDOC 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) antibodyALDOC 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 859CT9-5-3 unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (N-Term) antibodyALDOC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (AA 300-333) antibodyALDOC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (C-Term) antibodyALDOC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (AA 290-339) antibodyALDOC 适用: 人, 小鼠, 大鼠, 斑马鱼, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Aldolase C, Fructose-Bisphosphate (ALDOC) (N-Term) antibodyALDOC 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The antibody solution can be used at dilutions 1:1,000-2,000 for immunofluorescence. For western blots try at 1:2,000-5,000. A suitable control tissue is brain cell lysates.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4°C short term or -20°C long term.
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- ALDOC (Aldolase C, Fructose-Bisphosphate (ALDOC))
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别名
- Aldolase C
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背景
- Aldolases are glycolytic enzymes that catalyze the reversible aldol cleavage of fructose 1,6-bisphosphate and fructose-1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde 3-phosphate or glyceraldehyde, respectively. Three aldolase isozymes are found in mammals, specifically aldolases A, B, and C, each of which is encoded by a separate gene.Aldolase A is generally considered to be a muscle enzyme. Northern analysis of cultured cells suggests that it is present in both neurons and glia. Aldolase B is considered to be a liver-specific enzyme and it is transcriptionally activated by signals from hormones and dietary factors. In the adult, aldolase C is the brain-specific isozyme, with low but detectable activity in fetal tissues. Aldolase C shares 81% amino acid identity with aldolase A and 70% identity with aldolase B. Earlier studies using isozyme-specific antibodies report its location in gray matter astrocytes and cells of the pia mater. In situ hybridization of mouse central nervous system using isozyme-specific probes revealed that aldolase A and C are expressed in complementary cell types: aldolase A mRNA is found in neurons, aldolase C message is detected in astrocytes, some cells of the pia mater, and Purkinje cells. Aldolase C can in some situations be used as an astrocyte marker. However Purkinje cells of the cerebellum contain high levels of the enzyme, so the enzyme is not totally astrocyte specific. MCA-1A1 was raised against C-terminal 23 amino acids of the human aldolase C protein, the sequence is KYEGSGEDGGAAAQSLYIANHAY. The HGNC name for this protein is ALDOC.
抗原
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