14-3-3 eta 抗体
Quick Overview for 14-3-3 eta 抗体 (ABIN1580407)
抗原
See all 14-3-3 eta (YWHAH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- affinity purified antibody
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亚型
- IgG1
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anti-14-3-3 eta (YWHAH) (AA 4-246) antibody
YWHAH 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) antibodyYWHAH 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) (AA 72-121) antibodyYWHAH 适用: 人, 小鼠, 大鼠, 猴, Cow, 兔, 犬, 斑马鱼, 小鸡, 非洲爪蟾, Bat, 豚鼠, 马, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) (AA 1-246) antibodyYWHAH 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) (N-Term) antibodyYWHAH 适用: 人, 兔, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) (AA 71-170) antibodyYWHAH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) (AA 71-170) antibodyYWHAH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6A12 unconjugated
anti-14-3-3 eta (YWHAH) (Internal Region) antibodyYWHAH 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) (N-Term) antibodyYWHAH 适用: 人, 小鼠, 大鼠, Cow, 兔, 小鸡, 非洲爪蟾 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 eta (YWHAH) (Center) antibodyYWHAH 适用: 人, 小鼠, 大鼠, 猴, Cow WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Try at dilutions of 1:500-1:1,000 for immunofluorescence. For western blots try at 1:1,000-1:5,000. A suitable control tissue is rat spinal cord or peripheral nerve homogenate.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4°C short term or -20°C long term.
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- 14-3-3 eta (YWHAH)
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别名
- 14-3-3eta
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背景
- The 14.3.3 family of proteins were originally discovered as prominent protein spots on 2 dimensional gels. They are a family of 28-33 kDa proteins which are often major proteins of the cytoplasm. They function as binding partners for phosphoserine and phosphothreonine sites in other proteins, though they have other binding partners which are not dependent on phosphorylation. These binding interactions are important in the regulation of molecules such as the signaling kinases in the MAP kinase pathway, c-Raf and b-Raf, the proapoptotic molecules Bad and Bax, and the cell cycle regulator Cdc25. There are 7 mammalian 14.3.3 proteins and they are normally expressed as homo or in some cases heterodimers. 14.3.3 eta is widely expressed and concentrated in the nervous system. The HGNC name for 14.3.3 is YWHAH, and an alternate name is tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein 1, due to a role for this protein in activation of tyrosine and tryptophan hydroxylases. One result of this is that the HGNC name is YWHAH. The 14.3.3eta, protein accumulates in the CSF of patients suffering form Creutzfeld Jacob Disease, and can be used for the diagnosis of this disease. Furthermore, this protein binds alpha,-synuclein in the Lewy bodies of Parkinson's disease and has been linked to early-onset schizopherenia. The HGNC name for this protein is YWHAH. ﾠ
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction
抗原
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