DBN1 抗体 (AA 1-326) (PE)
(1 reference)Quick Overview for DBN1 抗体 (AA 1-326) (PE) (ABIN1558085)
抗原
See all DBN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-326
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原理
- Anti-Drebrin PE
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特异性
- The mouse monoclonal antibody DBN-N-03 recognizes drebrin, an approximately 100-125 kDa intracellular regulator of actin cytoskeleton.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)
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亚型
- IgG2b
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anti-Drebrin 1 (DBN1) (AA 150-281) antibody
DBN1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DBN1-2879 unconjugated
anti-Drebrin 1 (DBN1) (Internal Region) antibodyDBN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 1-649) antibodyDBN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Drebrin 1 (DBN1) (AA 1-326) antibodyDBN1 适用: 人 WB, FACS, MS 宿主: 小鼠 Monoclonal DBN-N-03 unconjugated
anti-Drebrin 1 (DBN1) (AA 401-596) antibodyDBN1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 350-649) antibodyDBN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 3-134) antibodyDBN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 151-250) antibodyDBN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 194-228) antibodyDBN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56246 unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
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限制
- 仅限研究用
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溶解方式
- No reconstitution is necessary.
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody." in: Leukemia research, Vol. 35, Issue 8, pp. 1111-3, (2011) (PubMed).
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: "High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody." in: Leukemia research, Vol. 35, Issue 8, pp. 1111-3, (2011) (PubMed).
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- DBN1 (Drebrin 1 (DBN1))
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别名
- Drebrin
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背景
- Drebrin 1,Drebrin is an actin-binding protein, which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling, affecting especially intercellular junctions, such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome, and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.,DBN, D0S117E
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基因ID
- 1627
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UniProt
- Q16643
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途径
- Maintenance of Protein Location
抗原
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