cGMP
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 488
应用备注
1: 10-50 dilutions for nonradioactive EIA assays (10 μL/assay in an 70 μL assay reaction). The material is sufficient for performing 100-500 nonradioactive EIA assays or 6,000 radioactive assays. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
状态
Liquid
缓冲液
PBS, 0.02 % Thimerosal, 50 % Glycerol, 1 % BSA
储存液
Thimerosal (Merthiolate)
注意事项
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C/-80 °C
储存方法
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
抗原
Cyclic GMP (cGMP)
别名
Cyclic GMP
物质类
Chemical
背景
Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).Synonyms: cGMP, cyclic guanosine monophosphate