HMOX2 抗体
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北京 101111
Quick Overview for HMOX2 抗体 (ABIN155125)
抗原
See all HMOX2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes ~36 kDa Heme-Oxygenase-2.
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纯化方法
- Immunoaffinity purified
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免疫原
- Synthetic peptide surrounding amino acid 25 of human HO-2
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应用备注
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Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry on frozen sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))
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别名
- Heme Oxygenase 2 (HMOX2)
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背景
- Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two heme oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. At the amino acid level, HO-1 and HO-2 are 42 % homologous. However, each isozyme is evolutionary highly conserved. HO-1 is the inducible form of the enzyme and is therefore also referred to as stress protein Hsp32. Expression of HO-1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO-2 is the constituitive form of the enzyme. It is not inducible by exogeneous stimuli and HO-2 is the most prevalent form in most tissues, except the spleen where HO-1 levels are predominant under normal conditions.Synonyms: HO-2, HO2
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基因ID
- 3163
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NCBI登录号
- NP_001120676
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UniProt
- P30519
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途径
- Transition Metal Ion Homeostasis
抗原
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