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GSTM1 抗体 (AA 184-211)

This anti-GSTM1 antibody is a 小鼠 单克隆 antibody detecting GSTM1 in WB. Suitable for 人.
产品编号 ABIN1539938
发货至: 中国

Quick Overview for GSTM1 抗体 (AA 184-211) (ABIN1539938)

抗原

See all GSTM1 抗体
GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

适用

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宿主

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小鼠

克隆类型

  • 67
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单克隆

标记

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This GSTM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

524CT17-2-5
  • 抗原表位

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    AA 184-211

    纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    This GSTM1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 184-211 amino acids from human GSTM1.

    亚型

    IgM
  • 应用备注

    WB: 1:500~2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    GSTM1 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

    别名

    GSTM1

    背景

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

    分子量

    25712

    基因ID

    2944

    NCBI登录号

    NP_000552, NP_666533

    UniProt

    P09488

    途径

    Negative Regulation of Transporter Activity
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