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B-Cell Linker 抗体 (AA 150-178)

This 小鼠 单克隆 antibody specifically detects B-Cell Linker in WB. It exhibits reactivity toward 人.
产品编号 ABIN1539928
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for B-Cell Linker 抗体 (AA 150-178) (ABIN1539928)

抗原

See all B-Cell Linker (BLNK) 抗体
B-Cell Linker (BLNK)

适用

  • 114
  • 85
  • 55
  • 3
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  • 2
  • 2
  • 2
  • 1
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  • 1

宿主

  • 125
  • 7
  • 1
小鼠

克隆类型

  • 114
  • 19
单克隆

标记

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This B-Cell Linker antibody is un-conjugated

应用范围

  • 120
  • 52
  • 36
  • 28
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  • 20
  • 19
  • 9
  • 7
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB)

克隆位点

520CT6-1-1
  • 抗原表位

    • 25
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    • 5
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    AA 150-178

    纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    This BLNK antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from human BLNK.

    亚型

    IgM
  • 应用备注

    WB: 1:500~8000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    BLNK Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    B-Cell Linker (BLNK)

    别名

    BLNK

    背景

    This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    50466

    基因ID

    29760

    NCBI登录号

    NP_001107566, NP_001245369, NP_037446

    UniProt

    Q8WV28

    途径

    BCR Signaling
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