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MBP 抗体

The 小鼠 单克隆 anti-MBP antibody is suitable to detect MBP in samples from 人. It has been validated for WB 和 IF.
产品编号 ABIN1539854
发货至: 中国
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北京 101111
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Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MBP 抗体 (ABIN1539854)

抗原

MBP

适用

  • 79
  • 49
  • 46
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  • 2
  • 2

宿主

  • 72
  • 15
  • 2
  • 1
小鼠

克隆类型

  • 69
  • 21
单克隆

标记

  • 48
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  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
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  • 1
  • 1
This MBP antibody is un-conjugated

应用范围

  • 60
  • 29
  • 26
  • 26
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  • 25
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  • 22
  • 10
  • 7
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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

408CT17-4-3
  • 纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    Purified His-tagged MBP protein(Fragment) was used to produced this monoclonal antibody.

    亚型

    IgM
  • 应用备注

    IF: 1:10~50. WB: 1:5000~16000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    MBP Antibody (Ascites) can be refrigerated at 2-8Â °C for up to 6 months. For long term storage, keep at -20Â °C.

    有效期

    6 months
  • 抗原

    MBP

    背景

    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq].

    分子量

    33117

    基因ID

    4155

    NCBI登录号

    NP_001020252, NP_001020261, NP_001020263, NP_001020271, NP_001020272, NP_002376

    UniProt

    P02686
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