CLCF1 抗体 (N-Term)
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Quick Overview for CLCF1 抗体 (N-Term) (ABIN1539397)
抗原
See all CLCF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 46-72, N-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CLCF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 amino acids from the N-terminal region of human CLCF1.
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亚型
- Ig Fraction
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anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 88-190) antibody
CLCF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-225) antibodyCLCF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) antibodyCLCF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) antibodyCLCF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 29-225) antibodyCLCF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 1-225) antibodyCLCF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-178) antibodyCLCF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- CLCF1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
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别名
- CLCF1
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背景
- This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 25176
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基因ID
- 23529
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NCBI登录号
- NP_001159684, NP_037378
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UniProt
- Q9UBD9
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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