RCAN1 抗体 (N-Term)
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Quick Overview for RCAN1 抗体 (N-Term) (ABIN1539360)
抗原
See all RCAN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 41-68, N-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- RCAN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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别名
- RCAN1
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背景
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
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分子量
- 28079
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基因ID
- 1827
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NCBI登录号
- NP_004405, NP_981962, NP_981963
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UniProt
- P53805
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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