ITPK1 抗体 (N-Term)
Quick Overview for ITPK1 抗体 (N-Term) (ABIN1539261)
抗原
See all ITPK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 28-54, N-Term
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预测反应
- B, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ITPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human ITPK1.
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亚型
- Ig Fraction
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anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (AA 1-314) antibody
ITPK1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (AA 1-314) antibodyITPK1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) antibodyITPK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (AA 185-414) antibodyITPK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (AA 1-314) antibodyITPK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (AA 81-130) antibodyITPK1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (AA 36-85) antibodyITPK1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (AA 179-228) antibodyITPK1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (N-Term) antibodyITPK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- ITPK1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
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别名
- ITPK1
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背景
- Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.
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分子量
- 45621
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基因ID
- 3705
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NCBI登录号
- NP_001136065, NP_001136066, NP_055031
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UniProt
- Q13572
抗原
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