GRM7 抗体 (N-Term)
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Quick Overview for GRM7 抗体 (N-Term) (ABIN1539213)
抗原
See all GRM7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 240-269, N-Term
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GRM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the N-terminal region of human GRM7.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- GRM7 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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别名
- GRM7
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背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 102251
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基因ID
- 2917
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NCBI登录号
- NP_000835, NP_870989
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UniProt
- Q14831
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途径
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
抗原
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