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DMPK 抗体 (N-Term)

This anti-DMPK antibody is a 兔 多克隆 antibody detecting DMPK in WB. Suitable for 人.
产品编号 ABIN1538919
发货至: 中国

Quick Overview for DMPK 抗体 (N-Term) (ABIN1538919)

抗原

See all DMPK 抗体
DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

适用

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宿主

  • 53
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克隆类型

  • 55
  • 3
多克隆

标记

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This DMPK antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB36813
  • 抗原表位

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    AA 11-39, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DMPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human DMPK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    DMPK Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

    别名

    DMPK

    背景

    The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

    分子量

    69385

    基因ID

    1760

    NCBI登录号

    NP_001075029, NP_001075031, NP_001075032, NP_004400

    UniProt

    Q09013

    途径

    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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