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DROSHA 抗体 (AA 737-764)

DROSHA 适用: 人 WB 宿主: 兔 Polyclonal RB38658 unconjugated
产品编号 ABIN1538601
发货至: 中国
  • 抗原 See all DROSHA 抗体
    DROSHA (Drosha, Ribonuclease Type III (DROSHA))
    抗原表位
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 737-764
    适用
    • 55
    • 18
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 1
    • 1
    克隆类型
    • 46
    • 10
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    This DROSHA antibody is un-conjugated
    应用范围
    • 29
    • 19
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Rnasen antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-764 amino acids from the Central region of mouse Rnasen.
    克隆位点
    RB38658
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Mouse Rnasen Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    DROSHA (Drosha, Ribonuclease Type III (DROSHA))
    别名
    Rnasen (DROSHA 产品)
    别名
    im:7150667 antibody, zgc:158612 antibody, ETOHI2 antibody, HSA242976 antibody, RANSE3L antibody, RN3 antibody, RNASE3L antibody, RNASEN antibody, 1110013A17Rik antibody, AI874853 antibody, Etohi2 antibody, Rn3 antibody, Rnasen antibody, RGD1307626 antibody, ribonuclease type III, nuclear antibody, Ribonuclease 3 antibody, ribonuclease 3 antibody, drosha ribonuclease III antibody, drosha, ribonuclease type III antibody, rnasen antibody, Thicy_0885 antibody, Sinme_0866 antibody, Isova_2087 antibody, Sphch_0770 antibody, DROSHA antibody, Drosha antibody
    背景
    Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, RNASEN/DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies (By similarity).
    分子量
    158828
    基因ID
    14000
    NCBI登录号
    NP_001123621, NP_081075
    UniProt
    Q5HZJ0
    途径
    Regulatory RNA Pathways
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