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DROSHA 抗体 (AA 737-764)

DROSHA 适用: 人 WB 宿主: 兔 Polyclonal RB38658 unconjugated
产品编号 ABIN1538601
发货至: 中国
  • 抗原 See all DROSHA 抗体
    DROSHA (Drosha, Ribonuclease Type III (DROSHA))
    抗原表位
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 737-764
    适用
    • 44
    • 10
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 1
    克隆类型
    • 36
    • 9
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This DROSHA antibody is un-conjugated
    应用范围
    • 26
    • 16
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Rnasen antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-764 amino acids from the Central region of mouse Rnasen.
    克隆位点
    RB38658
    亚型
    Ig Fraction
    Top Product
    Discover our top product DROSHA Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Mouse Rnasen Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    DROSHA (Drosha, Ribonuclease Type III (DROSHA))
    别名
    Rnasen (DROSHA 产品)
    背景
    Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, RNASEN/DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies (By similarity).
    分子量
    158828
    基因ID
    14000
    NCBI登录号
    NP_001123621, NP_081075
    UniProt
    Q5HZJ0
    途径
    Regulatory RNA Pathways
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