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PCDHGB4 抗体 (AA 353-379)

This anti-PCDHGB4 antibody is a 兔 多克隆 antibody detecting PCDHGB4 in WB. Suitable for 人.
产品编号 ABIN1538347
发货至: 中国

Quick Overview for PCDHGB4 抗体 (AA 353-379) (ABIN1538347)

抗原

See all PCDHGB4 抗体
PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))

适用

宿主

  • 8
  • 1

克隆类型

  • 9
多克隆

标记

  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
This PCDHGB4 antibody is un-conjugated

应用范围

  • 9
  • 8
  • 1
Western Blotting (WB)

克隆位点

RB39608
  • 抗原表位

    • 6
    • 1
    • 1
    • 1
    • 1
    AA 353-379

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PCDHGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-379 amino acids from the Central region of human PCDHGB4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    PCDHGB4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))

    别名

    PCDHGB4

    背景

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.

    分子量

    99927

    基因ID

    8641

    NCBI登录号

    NP_003727, NP_115269

    UniProt

    Q9UN71
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