Otopetrin 2 抗体 (AA 336-363)
This anti-Otopetrin 2 antibody is a 兔 多克隆 antibody detecting Otopetrin 2 in WB. Suitable for 人.
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Quick Overview for Otopetrin 2 抗体 (AA 336-363) (ABIN1538326)
抗原
Otopetrin 2 (OTOP2)
适用
人
宿主
兔
克隆类型
多克隆
标记
This Otopetrin 2 antibody is un-conjugated
应用范围
Western Blotting (WB)
克隆位点
RB37737
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抗原表位
- AA 336-363
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This OTOP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the Central region of human OTOP2.
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亚型
- Ig Fraction
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anti-Otopetrin 2 (OTOP2) (AA 423-493) antibody
OTOP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F11 unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- OTOP2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- Otopetrin 2 (OTOP2)
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别名
- OTOP2
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背景
- Otopetrins are multi-transmembrane domain proteins that share conserved gene and protein structure and are possibly involved in the formation of otoconia and otoliths. Located in the utricle and saccule of the inner ear, otoconia are complex calcium carbonate biominerals that are required for the normal sensation of gravity and linear acceleration. Vertigo and loss of balance may be attributed to degeneration of displacement of otoconia. The otopetrin family consists of three proteins, OTOP1, OTOP2 and OTOP3. These proteins have 12 putative transmembrane domains that are clustered into three otopetrin domains (OD-I, II and III). OTOP1 was the first described member of the Otopetrin family. Mutations of OTOP1 leads to absence of otoconia or otoliths, though inner ear development is normal. OTOP2 and OTOP3 share significant structural similarity with OTOP1 and may also play a role in the formation of mineralized structures.
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分子量
- 62236
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基因ID
- 92736
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NCBI登录号
- NP_835454
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UniProt
- Q7RTS6
抗原
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