MCM8 抗体 (AA 322-350)
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Quick Overview for MCM8 抗体 (AA 322-350) (ABIN1538307)
抗原
See all MCM8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 322-350
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This MCM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the Central region of human MCM8.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- MCM8 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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别名
- MCM8
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背景
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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分子量
- 93697
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基因ID
- 84515
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NCBI登录号
- NP_001268449, NP_001268450, NP_001268451, NP_115874, NP_877954
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UniProt
- Q9UJA3
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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