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PDZD3 抗体 (AA 258-285)

This anti-PDZD3 antibody is a 兔 多克隆 antibody detecting PDZD3 in WB. Suitable for 人.
产品编号 ABIN1538201
发货至: 中国

Quick Overview for PDZD3 抗体 (AA 258-285) (ABIN1538201)

抗原

See all PDZD3 抗体
PDZD3 (PDZ Domain Containing 3 (PDZD3))

适用

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宿主

  • 21
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克隆类型

  • 23
  • 3
多克隆

标记

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This PDZD3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB37960
  • 抗原表位

    • 7
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    AA 258-285

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    PDZD3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    PDZD3 (PDZ Domain Containing 3 (PDZD3))

    别名

    PDZD3

    背景

    Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).

    基因ID

    79849

    NCBI登录号

    NP_001161940, NP_079067

    UniProt

    Q86UT5
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