This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This MARCH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-274 amino acids from the Central region of human MARCH10.
MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 [PubMed 17604280]).