LIM Domain Binding 3 Protein 抗体 (AA 235-262)
Quick Overview for LIM Domain Binding 3 Protein 抗体 (AA 235-262) (ABIN1538145)
抗原
See all LIM Domain Binding 3 Protein (LDB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 235-262
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LDB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-262 amino acids from the Central region of human LDB3.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- LDB3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
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别名
- LDB3
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背景
- This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq].
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分子量
- 77135
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基因ID
- 11155
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NCBI登录号
- NP_001073583, NP_001073584, NP_001073585, NP_001165081, NP_001165082, NP_009009
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UniProt
- O75112
抗原
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