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IL12B 抗体 (AA 196-222)

This anti-IL12B antibody is a 兔 多克隆 antibody detecting IL12B in WB. Suitable for 小鼠.
产品编号 ABIN1538036
发货至: 中国
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Quick Overview for IL12B 抗体 (AA 196-222) (ABIN1538036)

抗原

See all IL12B 抗体
IL12B (Interleukin 12 beta (IL12B))

适用

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  • 36
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  • 1
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小鼠

宿主

  • 98
  • 29
  • 11
  • 3
  • 2

克隆类型

  • 86
  • 57
多克隆

标记

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This IL12B antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB38646
  • 抗原表位

    • 15
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    • 1
    • 1
    • 1
    AA 196-222

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Il12b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-222 amino acids from the Central region of mouse Il12b.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Mouse Il12b Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    IL12B (Interleukin 12 beta (IL12B))

    别名

    Il12b

    背景

    Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (By similarity). Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

    分子量

    38235

    基因ID

    16160

    NCBI登录号

    NP_032378

    UniProt

    P43432

    途径

    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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