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NARF 抗体 (AA 134-160)

This 兔 多克隆 antibody specifically detects NARF in WB. It exhibits reactivity toward 人.
产品编号 ABIN1537831
发货至: 中国
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Quick Overview for NARF 抗体 (AA 134-160) (ABIN1537831)

抗原

See all NARF 抗体
NARF (Nuclear Prelamin A Recognition Factor (NARF))

适用

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宿主

  • 46
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克隆类型

  • 46
  • 1
多克隆

标记

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  • 1
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This NARF antibody is un-conjugated

应用范围

  • 35
  • 23
  • 13
  • 13
  • 4
  • 3
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  • 1
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Western Blotting (WB)

克隆位点

RB37217
  • 抗原表位

    • 16
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    • 1
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    AA 134-160

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This NARF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 amino acids from the Central region of human NARF.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    NARF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    NARF (Nuclear Prelamin A Recognition Factor (NARF))

    别名

    NARF

    背景

    Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.

    分子量

    51156

    基因ID

    26502

    NCBI登录号

    NP_001033707, NP_001077077, NP_036468, NP_114174

    UniProt

    Q9UHQ1
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