This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ARHGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human ARHGAP1.
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.