电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

FBXL19 抗体 (C-Term)

This anti-FBXL19 antibody is a 兔 多克隆 antibody detecting FBXL19 in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1537454
发货至: 中国

Quick Overview for FBXL19 抗体 (C-Term) (ABIN1537454)

抗原

See all FBXL19 抗体
FBXL19 (F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))

适用

  • 19
  • 11
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 18
  • 1

克隆类型

  • 18
  • 1
多克隆

标记

  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
This FBXL19 antibody is un-conjugated

应用范围

  • 13
  • 12
  • 2
Western Blotting (WB)

克隆位点

RB38770
  • 抗原表位

    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 543-570, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    FBXL19 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • Dong, Zhao, Wei, Bowser, Khoo, Liu, Luketich, Pennathur, Ma, Zhao: "F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation." in: Molecular cancer, Vol. 13, pp. 76, (2014) (PubMed).

    Wei, Mialki, Dong, Khoo, Mallampalli, Zhao, Zhao: "A new mechanism of RhoA ubiquitination and degradation: Roles of SCF(FBXL19) E3 ligase and Erk2." in: Biochimica et biophysica acta, (2013) (PubMed).

    Zhao, Mialki, Wei, Coon, Zou, Chen, Mallampalli, Zhao: "SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 7, pp. 2611-9, (2013) (PubMed).

  • 抗原

    FBXL19 (F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))

    别名

    FBXL19

    背景

    Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

    分子量

    75707

    基因ID

    54620

    NCBI登录号

    NP_001093254, NP_001269280

    UniProt

    Q6PCT2
You are here:
Chat with us!