FBXL19 抗体 (C-Term)
There are 3+ publications for this product available. The 兔 多克隆 anti-FBXL19 antibody is suitable to detect FBXL19 in samples from 人. It has been validated for WB.
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(3 references)
产品编号 ABIN1537454
发货至:
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Quick Overview for FBXL19 抗体 (C-Term) (ABIN1537454)
抗原
See all FBXL19 抗体
FBXL19
(F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))
适用
人
宿主
兔
克隆类型
多克隆
标记
This FBXL19 antibody is un-conjugated
应用范围
Western Blotting (WB)
克隆位点
RB38770
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抗原表位
- AA 543-570, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.
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亚型
- Ig Fraction
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anti-F-Box and Leucine-Rich Repeat Protein 19 (FBXL19) (AA 365-472) antibody
FBXL19 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 19 (FBXL19) (AA 4-259) antibodyFBXL19 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- FBXL19 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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: "F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation." in: Molecular cancer, Vol. 13, pp. 76, (2014) (PubMed).
: "A new mechanism of RhoA ubiquitination and degradation: Roles of SCF(FBXL19) E3 ligase and Erk2." in: Biochimica et biophysica acta, (2013) (PubMed).
: "SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 7, pp. 2611-9, (2013) (PubMed).
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: "F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation." in: Molecular cancer, Vol. 13, pp. 76, (2014) (PubMed).
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- FBXL19 (F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))
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别名
- FBXL19
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背景
- Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
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分子量
- 75707
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基因ID
- 54620
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NCBI登录号
- NP_001093254, NP_001269280
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UniProt
- Q6PCT2
抗原
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