Apoptosis Inhibitor 5 抗体 (C-Term)
Quick Overview for Apoptosis Inhibitor 5 抗体 (C-Term) (ABIN1537392)
抗原
See all Apoptosis Inhibitor 5 (API5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 482-510, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This API5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-510 amino acids from the C-terminal region of human API5.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- API5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- Apoptosis Inhibitor 5 (API5)
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别名
- API5
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背景
- Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
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分子量
- 59005
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基因ID
- 8539
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NCBI登录号
- NP_001136402, NP_001136403, NP_001230676, NP_006586
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UniProt
- Q9BZZ5
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途径
- Growth Factor Binding
抗原
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