Zona Pellucida Glycoprotein 3 抗体 (C-Term)
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Quick Overview for Zona Pellucida Glycoprotein 3 抗体 (C-Term) (ABIN1537191)
抗原
See all Zona Pellucida Glycoprotein 3 (ZP3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 353-380, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ZP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of human ZP3.
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亚型
- Ig Fraction
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anti-Zona Pellucida Glycoprotein 3 (ZP3) (AA 250-350) antibody
ZP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 3 (ZP3) (AA 1-373) antibodyZP3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) antibodyZP3 适用: 人, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) antibodyZP3 适用: 人, 大鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- ZP3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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: "Serum antibody immunoreactivity to equine zona protein after SpayVac vaccination." in: Theriogenology, Vol. 84, Issue 2, pp. 261-7, (2015) (PubMed).
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: "Serum antibody immunoreactivity to equine zona protein after SpayVac vaccination." in: Theriogenology, Vol. 84, Issue 2, pp. 261-7, (2015) (PubMed).
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- Zona Pellucida Glycoprotein 3 (ZP3)
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别名
- ZP3
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背景
- The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus, however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene.
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分子量
- 47018
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基因ID
- 7784
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NCBI登录号
- NP_001103824, NP_009086
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UniProt
- P21754
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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