GNAS 抗体 (C-Term)
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Quick Overview for GNAS 抗体 (C-Term) (ABIN1536863)
抗原
See all GNAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 217-244, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human GNAS.
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亚型
- Ig Fraction
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anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A2B7 unconjugated
anti-GNAS Complex Locus (GNAS) (N-Term) antibodyGNAS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) antibodyKO Validated GNAS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 42-188) antibodyGNAS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G6G5 unconjugated
anti-GNAS Complex Locus (GNAS) (N-Term) antibodyGNAS 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 1-394) antibodyGNAS 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 310-404) antibodyGNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (Internal Region) antibodyVerified GNAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 287-315), (C-Term) antibodyGNAS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33001 unconjugated
anti-GNAS Complex Locus (GNAS) (AA 286-315), (C-Term) antibodyGNAS 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- GNAS Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- GNAS (GNAS Complex Locus (GNAS))
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别名
- GNAS
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背景
- This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contains a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
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分子量
- 28029
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基因ID
- 2778
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NCBI登录号
- NP_057676
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UniProt
- O95467
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途径
- Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
抗原
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