LIN7A 抗体 (C-Term)
Quick Overview for LIN7A 抗体 (C-Term) (ABIN1536800)
抗原
See all LIN7A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 180-207, C-Term
-
预测反应
- B, M, Rat
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This LIN7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-207 amino acids from the C-terminal region of human LIN7A.
-
亚型
- Ig Fraction
-
-
anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibody
LIN7A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibodyLIN7A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lin-7 Homolog A (LIN7A) (AA 1-90) antibodyLIN7A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- LIN7A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
-
有效期
- 6 months
-
-
- LIN7A (Lin-7 Homolog A (LIN7A))
-
别名
- LIN7A
-
背景
- LIN7A plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
-
分子量
- 25997
-
基因ID
- 8825
-
NCBI登录号
- NP_004655
-
UniProt
- O14910
-
途径
- Synaptic Membrane
抗原
-
