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MMP17 抗体 (Cleaved-Gln129)

This 兔 多克隆 antibody specifically detects MMP17 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1536144
发货至: 中国
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Quick Overview for MMP17 抗体 (Cleaved-Gln129) (ABIN1536144)

抗原

See all MMP17 抗体
MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

适用

  • 69
  • 28
  • 20
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 68
  • 2
兔

克隆类型

  • 51
  • 19
多克隆

标记

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  • 3
  • 3
  • 3
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  • 1
  • 1
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  • 1
  • 1
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This MMP17 antibody is un-conjugated

应用范围

  • 54
  • 27
  • 22
  • 13
  • 13
  • 11
  • 11
  • 8
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
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    • 1
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    AA 110-159, Cleaved-Gln129

    原理

    Cleaved-MMP-17 (Q129) Antibody

    特异性

    Cleaved-MMP-17 (Q129) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-17 protein resulting from cleavage adjacent to Q129.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MMP17. AA range:110-159

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

    别名

    MMP17

    背景

    Synonyms: MMP17, MT4MMP, Matrix metalloproteinase-17, MMP-17, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP

    Background: This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers. [provided by RefSeq, Jan 2016],

    Gene Name: MMP17

    Protein Name: Matrix metalloproteinase-17

    分子量

    53 kDa

    基因ID

    4326

    OMIM

    602285

    UniProt

    Q9ULZ9
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