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MMP1 抗体 (Cleaved-Phe100)

The 兔 多克隆 anti-MMP1 antibody (ABIN1536140) specifically detects MMP1 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1536140
发货至: 中国
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Quick Overview for MMP1 抗体 (Cleaved-Phe100) (ABIN1536140)

抗原

See all MMP1 抗体
MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

适用

  • 135
  • 12
  • 12
  • 8
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 122
  • 20
  • 3
兔

克隆类型

  • 107
  • 38
多克隆

标记

  • 75
  • 9
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MMP1 antibody is un-conjugated

应用范围

  • 127
  • 61
  • 47
  • 40
  • 33
  • 24
  • 21
  • 17
  • 13
  • 13
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 13
    • 13
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-130, Cleaved-Phe100

    原理

    Cleaved-MMP-1 22k (F100) Antibody

    特异性

    Cleaved-MMP-1 22k (F100) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-1 22k protein resulting from cleavage adjacent to F100.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MMP1. AA range:81-130

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

    别名

    MMP1

    背景

    Synonyms: MMP1, CLG, Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1

    Background: matrix metallopeptidase 1(MMP1) Homo sapiens This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],

    Gene Name: MMP1

    Protein Name: Interstitial collagenase

    分子量

    19 kDa

    基因ID

    4312

    OMIM

    120353

    UniProt

    P03956
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