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ITGA6 抗体 (Cleaved-Glu942)

The 兔 多克隆 anti-ITGA6 antibody (ABIN1536134) specifically detects ITGA6 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1536134
发货至: 中国
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Quick Overview for ITGA6 抗体 (Cleaved-Glu942) (ABIN1536134)

抗原

See all ITGA6 抗体
ITGA6 (Integrin, alpha 6 (ITGA6))

适用

  • 153
  • 67
  • 49
  • 14
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  • 7
  • 6
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  • 1
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人, 小鼠, 大鼠

宿主

  • 102
  • 45
  • 17
  • 2
兔

克隆类型

  • 84
  • 80
多克隆

标记

  • 82
  • 15
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  • 5
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  • 3
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This ITGA6 antibody is un-conjugated

应用范围

  • 89
  • 62
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  • 35
  • 25
  • 22
  • 13
  • 13
  • 13
  • 12
  • 12
  • 3
  • 2
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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 13
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
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    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 923-972, Cleaved-Glu942

    原理

    Cleaved-Integrin α6 LC (E942) Antibody

    特异性

    Cleaved-Integrin α6 LC (E942) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α6 LC protein resulting from cleavage adjacent to E942.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ITGA6. AA range:923-972

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ITGA6 (Integrin, alpha 6 (ITGA6))

    别名

    ITGA6

    背景

    Synonyms: ITGA6, Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD antigen CD49f

    Background: integrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

    Gene Name: ITGA6

    Protein Name: Integrin alpha-6

    分子量

    28 kDa

    基因ID

    3655

    OMIM

    147556

    UniProt

    P23229

    途径

    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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