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CPT1C 抗体 (Cleaved-Thr288)

The 兔 多克隆 anti-CPT1C antibody is suitable to detect CPT1C in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN1536112
发货至: 中国
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Quick Overview for CPT1C 抗体 (Cleaved-Thr288) (ABIN1536112)

抗原

See all CPT1C 抗体
CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

适用

人, 小鼠, 大鼠

宿主

  • 53
  • 1
  • 1
兔

克隆类型

  • 54
  • 1
多克隆

标记

  • 23
  • 4
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  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CPT1C antibody is un-conjugated

应用范围

  • 40
  • 24
  • 13
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  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 7
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    • 2
    • 2
    • 2
    • 1
    • 1
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    AA 239-288, Cleaved-Thr288

    原理

    Cleaved-Cathepsin L1 HC (T288) Antibody

    特异性

    Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L1 HC protein resulting from cleavage adjacent to T288.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CATL1. AA range:239-288

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

    别名

    CATL1

    背景

    Synonyms: CTSL1, CTSL, Cathepsin L1, Major excreted protein, MEP

    Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012],

    Gene Name: CTSL1

    Protein Name: Cathepsin L1

    分子量

    30 kDa

    基因ID

    1514

    OMIM

    116880

    UniProt

    P07711

    途径

    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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