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SPTAN1 抗体 (Cleaved-Asp1185)

This 兔 多克隆 antibody specifically detects SPTAN1 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1536099
发货至: 中国
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Quick Overview for SPTAN1 抗体 (Cleaved-Asp1185) (ABIN1536099)

抗原

See all SPTAN1 抗体
SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

适用

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人, 小鼠, 大鼠

宿主

  • 125
  • 44
  • 1
兔

克隆类型

  • 106
  • 64
多克隆

标记

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This SPTAN1 antibody is un-conjugated

应用范围

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  • 14
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  • 11
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Western Blotting (WB), ELISA
  • 抗原表位

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    • 5
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    • 2
    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
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    AA 1136-1185, Cleaved-Asp1185

    原理

    Cleaved-Spectrin α II (D1185) Antibody

    特异性

    Cleaved-Spectrin α II (D1185) Polyclonal Antibody detects endogenous levels of fragment of activated Spectrin α II protein resulting from cleavage adjacent to D1185.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human SPTA2. AA range:1136-1185

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

    别名

    SPTA2

    背景

    Synonyms: SPTAN1, NEAS, SPTA2, Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit

    Background: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement.This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010],

    Gene Name: SPTAN1

    Protein Name: Spectrin alpha chain non-erythrocytic 1

    分子量

    137 kDa

    基因ID

    6709

    OMIM

    182810

    UniProt

    Q13813

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
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