AVPR1B 抗体 (AA 275-324)
Our Local Distributor
北京 101111
Quick Overview for AVPR1B 抗体 (AA 275-324) (ABIN1536013)
抗原
See all AVPR1B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 275-324
-
原理
- AVP Receptor V3 Antibody
-
特异性
- AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
-
别名
- AVPR1B
-
背景
-
Synonyms: AVPR1B, AVPR3, VPR3, Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor
Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],
Gene Name: AVPR1B
Protein Name: Vasopressin V1b receptor
-
分子量
- 46 kDa
-
基因ID
- 553
-
OMIM
- 600264
-
UniProt
- P47901
-
途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
-