PTAFR 抗体 (AA 194-243)
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北京 101111
Quick Overview for PTAFR 抗体 (AA 194-243) (ABIN1535986)
抗原
See all PTAFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 194-243
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原理
- PAF-R Antibody
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特异性
- PAF-R Polyclonal Antibody detects endogenous levels of PAF-R protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PTAFR. AA range:194-243
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亚型
- IgG
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anti-Platelet-Activating Factor Receptor (PTAFR) (AA 231-342) antibody
PTAFR 适用: 人 WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Receptor (PTAFR) (AA 297-342) antibodyPTAFR 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Receptor (PTAFR) (AA 1-342) antibodyPTAFR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Platelet-Activating Factor Receptor (PTAFR) (AA 259-274), (Extracellular), (Loop 3) antibodyPTAFR 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Receptor (PTAFR) (AA 259-274), (Extracellular), (Loop 3) antibody (FITC)PTAFR 适用: 小鼠 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-Platelet-Activating Factor Receptor (PTAFR) (AA 286-312), (C-Term) antibodyPTAFR 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB26788 unconjugated
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应用备注
- IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PTAFR (Platelet-Activating Factor Receptor (PTAFR))
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别名
- PTAFR
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背景
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Synonyms: PTAFR, PAFR, Platelet-activating factor receptor, PAF-R, PAFr
Background: This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],
Gene Name: PTAFR
Protein Name: Platelet-activating factor receptor
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分子量
- 39 kDa
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基因ID
- 5724
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OMIM
- 173393
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UniProt
- P25105
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
抗原
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