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Metabotropic Glutamate Receptor 5 抗体 (AA 21-70)

The 兔 多克隆 anti-Metabotropic Glutamate Receptor 5 antibody (ABIN1535756) specifically detects Metabotropic Glutamate Receptor 5 in WB, IHC, IF 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1535756
发货至: 中国
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Quick Overview for Metabotropic Glutamate Receptor 5 抗体 (AA 21-70) (ABIN1535756)

抗原

See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体
Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

适用

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  • 108
  • 95
  • 4
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  • 1
  • 1
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  • 1
人, 大鼠, 小鼠

宿主

  • 121
  • 43
  • 2
  • 1
  • 1
兔

克隆类型

  • 104
  • 64
多克隆

标记

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  • 5
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  • 1
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This Metabotropic Glutamate Receptor 5 antibody is un-conjugated

应用范围

  • 144
  • 72
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  • 14
  • 14
  • 9
  • 3
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

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    • 5
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    • 1
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    AA 21-70

    原理

    mGluR5 Antibody

    特异性

    MGluR5 Polyclonal Antibody detects endogenous levels of mGluR5 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GRM5. AA range:21-70

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

    别名

    GRM5

    背景

    Synonyms: GRM5, GPRC1E, MGLUR5, Metabotropic glutamate receptor 5, mGluR5

    Background: glutamate metabotropic receptor 5(GRM5) Homo sapiens This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

    Gene Name: GRM5

    Protein Name: Metabotropic glutamate receptor 5

    分子量

    132 kDa

    基因ID

    2915

    OMIM

    604102

    UniProt

    P41594

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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